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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK7
All Species:
21.52
Human Site:
T287
Identified Species:
31.56
UniProt:
P50613
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50613
NP_001790.1
346
39038
T287
P
C
A
R
I
T
A
T
Q
A
L
K
M
K
Y
Chimpanzee
Pan troglodytes
XP_518193
305
34323
M251
T
A
T
Q
A
L
K
M
K
Y
F
S
N
R
P
Rhesus Macaque
Macaca mulatta
XP_001092242
346
39008
T287
P
C
A
R
I
T
A
T
Q
A
L
K
M
K
Y
Dog
Lupus familis
XP_850424
354
39795
T295
P
C
T
R
I
T
A
T
Q
A
L
K
T
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q03147
346
38950
S287
P
C
T
R
T
T
A
S
Q
A
L
K
T
K
Y
Rat
Rattus norvegicus
P51952
329
37122
T277
F
N
P
C
T
R
I
T
A
S
Q
A
L
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506541
324
36280
T265
P
C
A
R
I
T
A
T
Q
A
L
K
T
K
Y
Chicken
Gallus gallus
P13863
303
34670
L249
P
K
W
K
P
G
S
L
G
T
H
V
Q
N
L
Frog
Xenopus laevis
P20911
352
39672
S293
P
C
A
R
C
T
A
S
Q
A
L
R
K
R
Y
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
R280
S
K
Q
R
I
S
A
R
Q
A
L
L
H
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511044
353
39655
R287
P
L
R
R
V
S
C
R
E
A
L
S
M
P
Y
Honey Bee
Apis mellifera
XP_395800
321
36188
D266
P
L
E
R
C
T
C
D
Q
A
L
Q
M
P
Y
Nematode Worm
Caenorhab. elegans
P34556
332
38277
K278
F
Y
D
K
K
T
G
K
H
L
L
D
D
T
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
P242
P
D
F
K
T
A
F
P
R
W
Q
A
Q
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
K284
P
K
A
R
I
S
I
K
Q
A
L
E
H
R
Y
Baker's Yeast
Sacchar. cerevisiae
P06242
306
35228
R253
P
P
S
R
D
E
L
R
K
R
F
I
A
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
99.7
92.6
N.A.
95
91
N.A.
87.5
39.8
85.2
42.2
N.A.
65.7
63.8
39.3
N.A.
Protein Similarity:
100
88.1
99.7
95.4
N.A.
96.8
92.4
N.A.
88.7
56.3
90.3
59.5
N.A.
78.4
75.1
57.5
N.A.
P-Site Identity:
100
0
100
86.6
N.A.
73.3
6.6
N.A.
93.3
6.6
66.6
46.6
N.A.
40
53.3
13.3
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
80
26.6
N.A.
93.3
20
86.6
53.3
N.A.
60
60
20
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
49.1
41
N.A.
Protein Similarity:
N.A.
57.8
N.A.
65.2
60.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
53.3
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
73.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
32
0
7
7
44
0
7
63
0
13
7
7
7
% A
% Cys:
0
38
0
7
13
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
7
0
0
7
0
0
0
7
7
7
0
% D
% Glu:
0
0
7
0
0
7
0
0
7
0
0
7
0
0
0
% E
% Phe:
13
0
7
0
0
0
7
0
0
0
13
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
7
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
0
13
0
0
% H
% Ile:
0
0
0
0
38
0
13
0
0
0
0
7
0
0
0
% I
% Lys:
0
19
0
19
7
0
7
13
13
0
0
32
7
32
0
% K
% Leu:
0
13
0
0
0
7
7
7
0
7
69
7
7
0
13
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
25
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
7
7
0
% N
% Pro:
75
7
7
0
7
0
0
7
0
0
0
0
0
19
7
% P
% Gln:
0
0
7
7
0
0
0
0
57
0
13
7
13
0
0
% Q
% Arg:
0
0
7
69
0
7
0
19
7
7
0
7
0
25
0
% R
% Ser:
7
0
7
0
0
19
7
13
0
7
0
13
0
0
7
% S
% Thr:
7
0
19
0
19
50
0
32
0
7
0
0
19
7
7
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
63
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _